pentobarbital decreases levels of ponatinib by affecting hepatic/intestinal enzyme CYP3A4 metabolism. Keep away from or Use Alternate Drug. Steer clear of Except the coadministration outweighs the probable chance of ponatinib underexposure; keep track of for indications of lowered efficacy.
pentobarbital will decrease the level or result of aripiprazole by affecting hepatic/intestinal enzyme CYP3A4 metabolism. Use Warning/Keep track of.
pentobarbital will lessen the extent or impact of flurbiprofen by affecting hepatic enzyme CYP2C9/10 metabolism. Insignificant/Significance Unfamiliar.
pentobarbital will reduce the extent or impact of cyclosporine by influencing hepatic/intestinal enzyme CYP3A4 metabolism. Use Caution/Monitor.
pentobarbital will lower the level or impact of losartan by affecting hepatic enzyme CYP2C9/10 metabolism. Minor/Importance Not known.
Contraindicated (one)pentobarbital decreases levels of vandetanib by affecting hepatic/intestinal enzyme CYP3A4 metabolism. Contraindicated. Stay away from coadministration with powerful CYP3A4 inducers; these drugs decrease publicity to vandetanib by as much as 40%.
pentobarbital will decrease the extent or effect of fruquintinib by impacting hepatic/intestinal enzyme CYP3A4 metabolism. Steer clear of or Use Alternate Drug. If coadministration with average CYP3A4 inducers is unavoidable, proceed to administer fruquintinib at proposed dosage.
pentobarbital will lower the extent or influence of venetoclax by influencing hepatic/intestinal enzyme CYP3A4 metabolism.
pentobarbital decreases levels of vandetanib by affecting hepatic/intestinal enzyme CYP3A4 metabolism. Contraindicated. Prevent coadministration with strong CYP3A4 inducers; these drugs decrease exposure to vandetanib by around 40%.
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pentobarbital will lessen the extent or effect of netupitant/palonosetron by impacting hepatic/intestinal enzyme CYP3A4 metabolism. Stay clear of or Use Alternate Drug. Netupitant is principally metabolized by CYP3A4; stay clear of use in sufferers who will be chronically employing a solid CYP3A4 inducer
Contraindicated (1)pentobarbital will decrease the extent or outcome of doravirine by influencing hepatic/intestinal enzyme CYP3A4 metabolism.
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